This Starmada campaign would be played as a multi-player multi-round round-robin tournament. Between each round you would advance the timeline and build new factions using the DP system in the Starmada Compendium. Each round you would get more DPs and more technology would become available for purchase.
Round one would feature a near-future interplanetary-only setting with extremely low technology. Factions would mostly be real-world political factions (NASA, ESU, and Chinese vessels, for example) and possibly extraterrestrial polities (The Free Asteroids, for example). Maybe start players out with negative DPs so that they are forced to take lower tech levels to buy nifty guns. battles at this level would be extremely small, say use the "small battle" points column but only roll d6+1. Only tech items that are arguably realworld extrapolations may be used. (I'd obviously have to draw up a list.) Each player would then fight one "key battle from history" with each other player, giving each player 1 point for a minor victory and 2 points for a major victory.
Each succeeding round the battles would get a little bigger, more technologies would become available, and each faction would get more DPs. I imagine that new factions would be created regularly. Perhaps the lowest scoring players would assume to have their factions destroyed while the higher scoring factions could opt to run a new faction.
My gut instincts tell me to run at least two rounds before introducing aliens into the mix. Certain technologies could be reserved for the aliens (e.g. organic hulls).